Guide

What is compounded semaglutide?

A pharmacy-prepared version of semaglutide that is not FDA-approved and not the same as Wegovy or Ozempic.

Compounded semaglutide is prepared by a licensed pharmacy, often as a vial requiring self-measured dosing. It is not FDA-approved, not reviewed for safety/effectiveness/quality before marketing, and not interchangeable with Wegovy or Ozempic. With the shortage resolved, lawful compounding is now narrow.

Regulatory status

Compounded GLP-1 in 2026

Regulatory status

Compounded GLP-1 in 2026

The FDA resolved the tirzepatide (Dec 2024) and semaglutide (Feb 2025) shortages, and wind-down deadlines passed in 2025. On Apr 30, 2026 the FDA proposed excluding these drugs from the 503B bulks list (comment closed Jun 29, 2026). Patient-specific 503A compounding continues only narrowly, and cost alone is not a clinical need. Full regulatory status →